If you try to install your ClickOnce application and get errors like this I’ll show you what Microsoft recomends you to do:
SUMMARY
Below is a summary of the errors, details of these errors are listed later in the log.
* Activation of http://xxx.xxx.xxx.xxx/App.application resulted in exception. Following failure messages were detected:
+ Failed while downloading http://xxx.xxx.xxx.xxx/App.exe.manifest
+ The remote server returned an error: (404) Not Found.
Your problem is probably that your deployment contain files that the webserver (if a webserver installation) doesn’t support download. The fix is to change the mime types to the current webserver. Read the rest of this entry »